GLOBAL DEFORMABLE SURFACE OPTIMIZATION USING ADAPTIVE CONSTRAINTS AND PENALTIES
Deformable models are able to solve surface extraction problems challenged by image noise because imageindependent constraints are used to regularize the shape of the extracted surface. However, this ability of deformable models is shadowed by their application specificity, initialization sensitivity and the difficulty of the selection of proper values for user definable parameters. To overcome these problems restricting the automation of surface extraction, we present a new algorithm, named AdaCoP, for the global minimization of the energy of deformable surfaces. It iteratively performs constrained local minimizations of the energy. It avoids the detection of the same local minimum multiple times by constraining the local optimizations in an adaptive manner. AdaCoP escapes from local minima by imposing an adaptive penalty energy to it. These constraints and penalties prevent the convergence to the local minima already found. The performance of the AdaCoP algorithm is relatively independent on the nature of the underlying image as well as the shape of the surface to be extracted. The performance of the algorithm is evaluated by extracting surfaces from synthetic images. Moreover, the good properties of the algorithm are demonstrated by considering applications within the automated analysis of positron emission tomography images. Although AdaCoP cannot be proven to converge to the global minimum, it is insensitive to its initialization and it therefore provides a way to automate surface extraction problems within medical image analysis.
energy minimization; medical image analysis; positron emission tomography; segmentation; surface extraction
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