STEREOLOGICAL ANALYSIS OF THE COCHLEAR NUCLEI OF MONKEY (MACACA FASCICULARIS) AFTER DEAFFERENTATION

Ana M Insausti, Ricardo Insausti, Luis M Cruz-Orive, Manuel Manrique

Abstract

The cochlear nuclei (CN) in the brainstem receive the input signals from the inner ear through the cochlear nerve, and transmit these signals to higher auditory centres. A variety of lesions of the cochlear nerve cause deafness. As reported in the literature, artificial removal of auditive input, or 'deafferentation', induces structural alterations in the CN. The purpose of this study was to estimate a number of relevant stereological parameters of the CN in control and deafferented Macaca fascicularis monkeys.

Keywords
Cavalieri estimator; cochlear nuclei; deafferentation; glia; nonhuman primate; stereology; vertical slices

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DOI: 10.5566/ias.v19.p133-137

Image Analysis & Stereology
EISSN 1854-5165 (Electronic version)
ISSN 1580-3139 (Printed version)